I've been struggling to find a decent way to do this as well, so I just came up with an idea (not a silver bullet, since this is mainly a matter of taste).
if bool(condition1 and
condition2 and
...
conditionN):
foo()
bar()
I find a few merits in this solution compared to others I've seen, namely, you get exactly an extra 4 spaces of indentation (bool), allowing all conditions to line up vertically, and the body of the if statement can be indented in a clear(ish) way. This also keeps the benefits of short-circuit evaluation of boolean operators, but of course adds the overhead of a function call that basically does nothing. You could argue (validly) that any function returning its argument could be used here instead of bool, but like I said, it's just an idea and it's ultimately a matter of taste.
Funny enough, as I was writing this and thinking about the "problem", I came up with yet another idea, which removes the overhead of a function call. Why not indicate that we're about to enter a complex condition by using extra pairs of parentheses? Say, 2 more, to give a nice 2 space indent of the sub-conditions relative to the body of the if statement. Example:
if (((foo and
bar and
frob and
ninja_bear))):
do_stuff()
I kind of like this because when you look at it, a bell immediatelly rings in your head saying "hey, there's a complex thing going on here!". Yes, I know that parentheses don't help readability, but these conditions should appear rarely enough, and when they do show up, you are going to have to stop and read them carefuly anyway (because they're complex).
Anyway, just two more proposals that I haven't seen here. Hope this helps someone :)