F18, F-18 or F.XVIII may refer to:
- McDonnell Douglas F/A-18 Hornet, an American all-weather carrier-capable multirole fighter jet
- Boeing F/A-18E/F Super Hornet, more advanced derivative of the F/A-18 Hornet
- F-18 (Michigan county highway)
- Fokker F.XVIII, a 1932 Dutch airliner
- HMS Zulu (F18), a 1937 British Royal Navy Tribal-class destroyer
- Formula 18, a class of catamaran
- Fluorine-18 (F-18 or F18F), an unstable isotope of fluorine
- Slip F-18, anchorage for the fictional houseboat The Busted Flush
See also
- The ICD-10 chapter V code for "Mental and behavioural disorders due to use of volatile solvents"
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