LIPN
Identifiers
AliasesLIPN, ARCI8, LI4, LIPL4, bA186O14.3, lipase family member N
External IDsOMIM: 613924 MGI: 1917416 HomoloGene: 66969 GeneCards: LIPN
Orthologs
SpeciesHumanMouse
Entrez

643418

70166

Ensembl

ENSG00000204020

ENSMUSG00000024770

UniProt

Q5VXI9

Q3U4B4

RefSeq (mRNA)

NM_001102469

NM_027340

RefSeq (protein)

NP_001095939

NP_081616

Location (UCSC)Chr 10: 88.76 – 88.78 MbChr 19: 34.04 – 34.06 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Lipase family member N is a protein that in humans is encoded by the LIPN gene. [5]

Function

The gene encodes a lipase that is highly expressed in granular keratinocytes in the epidermis, and plays a role in the differentiation of keratinocytes. Mutations in this gene are associated with lamellar ichthyosis type 4. [provided by RefSeq, Dec 2011].

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000204020 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000024770 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Lipase family member N". Retrieved 2019-12-02.

Further reading


This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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