It seems that the brutal shut down can be caused by OutOfMemoryException that caused failure in creating AppDomain that are needed for executing requests.
In this scenario Application_end won't be called.
Event Type: Error
Event Source: ASP.NET 2.0.50727.0
Event Category: None
Event ID: 1334
Date: 4/22/2012
Time: 11:23:13 AM
User: N/A
Computer: CCBSHAIS02
Description:
Failed to initialize the AppDomain:/LM/W3SVC/1/Root/AgentWS
Exception: System.SystemException
Message: Failed to create AppDomain.
StackTrace: at
System.Web.Hosting.ApplicationManager.CreateAppDomainWithHostingEnvironment(String
appId, IApplicationHost appHost, HostingEnvironmentParameters
hostingParameters) at
System.Web.Hosting.ApplicationManager.CreateAppDomainWithHostingEnvironmentAndReportErrors(String
appId, IApplicationHost appHost, HostingEnvironmentParameters
hostingParameters)
InnerException: System.OutOfMemoryException
Message: Exception of type 'System.OutOfMemoryException' was thrown.
StackTrace: at System.AppDomain.nCreateDomain(String friendlyName,
AppDomainSetup setup, Evidence providedSecurityInfo, Evidence
creatorsSecurityInfo, IntPtr parentSecurityDescriptor) at
System.AppDomain.CreateDomain(String friendlyName, Evidence
securityInfo, AppDomainSetup info) at
System.Web.Hosting.ApplicationManager.CreateAppDomainWithHostingEnvironment(String
appId, IApplicationHost appHost, HostingEnvironmentParameters
hostingParameters)
for further reading on IIS and AppDomains look at: http://weblogs.asp.net/owscott/archive/2007/09/02/application-vs-appdomain.aspx