Unfortunately, due to .NET's lack of an incremental GC (either in the MS or Mono implementation), building soft real-time software such as games with F# is problematic.
A few points here:
Incremental GCs are not the only way to get low pause times. Concurrent GCs like VCGC do the work in bulk but do it concurrently with mutators running, e.g. the VCGC implementation I described in the non-free article here was running with sub-millisecond pause times.
Incremental GC does not necessarily mean low pause times. For example, OCaml's GC typically incurs 10ms pauses and can incur arbitrarily-long pauses when it encounters a deep thread stack or long array in the heap.
I have measured typical pause times of 10ms with OCaml and 30ms with F# on .NET 3. With a simple implementation I was able to build a fault tolerant server in F# from scratch that handled 20k msgs/s with 50% of latencies under 114us and 95% under 500us.
I've written a language in F# that, if -
a) it doesn't perform adequately in the face of the generational GC (arbitrary pauses during the interactive simulation, and
I wouldn't give up on the platform is your first working version has unacceptable latency. There are lots of things you can do to bring the max latency down.
b) OCaml gets a good complete port to the LLVM backend -
I seriously doubt OCaml will ever get what I'd consider to be a "good complete port to the LLVM backend". They'll just retarget LLVM with the current typeless IR and it won't do much better than the current ocamlopt
compiler because LLVM isn't designed to optimize that kind of workload.
I will port it from F# to OCaml. I have avoided as much .NET-specific libraries as I could, and since F#'s syntax is based on OCaml's, I'm assuming there should be some automated tools to assist in converting the code.
No automated tools but I've ported hundreds of thousands of lines of code between OCaml and F# now and it is generally very easy because most code is written in the core ML subset of both languages.