I'm connecting to MS Word by win32com.client.Distpatch function and on the second request i've got error: 'CoInitialize has not been called.' I've found this topic:
http://www.velocityreviews.com/forums/t328097-coinitialize-error-when-using-adodbapi.html
and got that I have to call of CoInitialize in new thread. So question is where to call CoInitialize function in pyramid.