Dart supports interfacing with the native libraries (Ref: http://www.dartlang.org/articles/native-extensions-for-standalone-dart-vm/). There are some decent libraries available for socket communication, interfacing with databases and dealing with filesystems. Barring desktop GUI applications, I don't see any reason why it cannot be used as a general purpose language. What are advantages/disadvantages of Dart being used as a general purpose language (including performance)?
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Yes. Dart can be used as a general purpose programming language.
Advantages:
- It's fast, already faster than V8, and catching up to the JVM (Though it starts up much quicker).
- It's great for scripting on macos/linux. You can prefix a source file with #!/usr/bin/env dart
- Backed by a large team/company who are developing it in the open, along with an active community.
- Good documentation and articles.
Disadvantages:
- It's new. There are far more libraries available for Java, Python and node.js than for Dart.
- There are likely to be changes to the core IO libraries before it hits 1.0.
- No built-in support on cloud-hosting platforms, though there is a heroku buildpack.
Note you can build GUI applications using dart2js and chrome packaged apps.

Greg Lowe
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"fast, already faster than V8, and catching up to the JVM". Did you just describe beating Javascript as "fast". :-) – J D Jun 02 '16 at 21:10