I've recently decided to make a reasonably sized site using nanoc and Zurb Foundation myself, so I can tell you my thoughts on this:
A static site is a good idea in many situations, but they do have obvious limitations (with everything being static!). The typical use of a static generator like nanoc is for a blog, for which most of the limitations aren't a problem (especially with services like Disqus for comments). I personally decided to use nanoc to save hosting/maintenance costs initially (using Amazon S3 to host a static site is cheap and scalable compared to a VPS), because I don't need any of the dynamic stuff yet, and to learn something new!
I've written a few posts on my blog (link in my profile) about how I've integrated foundation from scratch with nanoc. I can't comment for bootstrap, but my steps were:
- Use the nanoc tutorial to create a site
- Use compass to integrate foundation into your site, by creating a
compass.rb
that has a require "zurb-foundation"
line as well as config for your asset paths (mine is here)
- Run a
compass install foundation -c compass.rb
to populate the foundation stylesheets, images and javascripts into your asset directories
- Update your
Rules
file to include compass, and process the stylesheets accordingly
That is a high-level overview - there's step-by-step detail on my blog if you're interested in going the foundation route.