OK, this is quite a very general question, and many answers are possible, none is definitive
because it's an ongoing research area. So far, the answers I have read mainly concern so-called "Vector-Space models", and your question is termed in a way that suggests such "statistical" approaches. Yet, if you want to avoid manipulating explicit term-document matrices, you might want to have a closer look at the Bayesian paradigm, which relies on
the same distributional hypothesis, but exploits a different theoretical framework: you don't manipulate any more raw distances, but rather probability distributions and, which is the most important, you can do inference based on them.
You mentioned LDA, I guess you mean Latent Dirichlet Allocation, which is the most well-known such Bayesian model to do document clustering. It is an alternative paradigm to vector space models, and a winning one: it has been proven to give very good results, which justifies its current success. Of course, one can argue that you still use kinds of term-document matrices through the multinomial parameters, but it's clearly not the most important aspect, and Bayesian researchers do rarely (if ever) use this term.
Because of its success, there are many software that implements LDA on the net. Here is one, but there are many others:
http://jgibblda.sourceforge.net/