In TFS 2013 there are 3 available templates.
Microsoft Visual Studio Scrum 2013
MSF for Agile Software Development 2013
MSF for CMMI Process Improvement 2013
Is there any significant difference using the Scrum template instead of MSF for Agile Software Development 2013?
In MSF for Agile Software Development 2013 there is iteration configuration possibility, but release and sprints are absent, while in Scrum there are both iterations and sprints.
Besides this, is there any other serious differences?