This is probably a long way around a simple problem, it does allow me to remove lines containing a number of matches. I did not have a partial match that could be used, and needed it to be done on over 1000 files.
This post did help me get to where I needed to, thank you.
$ParentPath = "C:\temp\test"
$Files = Get-ChildItem -Path $ParentPath -Recurse -Include *.txt
$Match1 = "matchtext1"
$Match2 = "matchtext2"
$Match3 = "matchtext3"
$Match4 = "matchtext4"
$Match5 = "matchtext5"
$Match6 = "matchtext6"
$Match7 = "matchtext7"
$Match8 = "matchtext8"
$Match9 = "matchtext9"
$Match10 = "matchtext10"
foreach ($File in $Files) {
$FullPath = $File | % { $_.FullName }
$OldContent = Get-Content $FullPath
$NewContent = $OldContent `
| Where-Object {$_ -notmatch $Match1} `
| Where-Object {$_ -notmatch $Match2} `
| Where-Object {$_ -notmatch $Match3} `
| Where-Object {$_ -notmatch $Match4} `
| Where-Object {$_ -notmatch $Match5} `
| Where-Object {$_ -notmatch $Match6} `
| Where-Object {$_ -notmatch $Match7} `
| Where-Object {$_ -notmatch $Match8} `
| Where-Object {$_ -notmatch $Match9} `
| Where-Object {$_ -notmatch $Match10}
Set-Content -Path $FullPath -Value $NewContent
Write-Output $File
}