On virtually every modern CPU, there are compare/jumpless and compare/jumplessequal instructions that take exactly the same amount of time, because it runs through exactly the same hardware modulo including or not the "equals" bit.
It is the case that computing the "not less than" (and therefoe "less than") is sort of free; for unsigned values, it is equivalent to carry from a twos's complement subtraction, which the CPUs already do. Computing equal is harder: the CPU has to determine that all bits of the result of the subtraction are zero; for 64 bits CPUs, that's naively a 64 bit and-gate which is pretty big and thus slow. The CPU designers know this, and build very fast networks to detect this quickly, precisely so it isn't a bottleneck.
So the answer is "NO", or to be clear, they take the same amount of time, and there are no compiler tricks to change that.