I use perl primarily for sysadmin support. So that's mostly - run lots of stuff on lots of servers type tasks, and the odd 'web page' front end.
I've been porting recently away from CGI towards Mojolicous with an nginx reverse proxy on the front end. The reason I picked it up in all honesty, because I liked the name (And any system that includes servers called 'morbo' and 'hypnotoad' is also rather fun).
Because I'm using nginx in front of it with a 'static ish' config, I can hook my http and https ports, and apply common standards for authentication, access and logging. But I can also run concurrently a combination of apps and static content (on multiple hosts if necessary).
Hypnotoad seems to work very nicely for running a preforking app instance, and morbo works well as a dev server. Because of the proxy, running 'pre-live review' on like for like infrastructure is also quite appealing.
I can't really offer much in the way of scalability and performance - that rather depends on a lot of other things. The stuff I'm doing is primarily data manipulation and graphing, so more disk IO based.