strptime() has no support for timezones.
So, you can make the conversion ignoring the timezone in the following way:
datetime.strptime("2015-07-17 06:01:51.066141", "%Y-%m-%d %I:%M:%S.%f").strftime("%s")
'1437102111'
Or in order to avoid using %s, as suggested below in the commments :
from datetime import datetime
(datetime.strptime("2015-07-17 06:01:51.066141", "%Y-%m-%d %I:%M:%S.%f") - datetime(1970, 1, 1)).total_seconds()
1437112911.066141
Notice this is a working version for Python 2, you can also check solutions for other versions here
Otherwise, you will have to use other libraries (django.utils or email.utils) that support timezones, or implement the timezone parsing on your own.
P.S. :
strptime docs appear to have support for timezone, but in fact it has not been implemented. Try :
datetime.strptime("2015-07-17 06:01:51.066141+00:00", "%Y-%m-%d %I:%M:%S.%f%z").strftime("%s")
and you will see that it is not supported. You can also verify it by searching more about strptime()