Disabling names on python level won't help as there are numerous ways around it. See this and this post for more info. This is what you need to do:
For CPython, use RestrictedPython to define a restricted subset of Python.
For PyPy, use sandboxing. It allows you to run arbitrary python code in a special environment that serializes all input/output so you can check it and decide which commands are allowed before actually running them.
Since version 3.8 Python supports audit hooks so you can completely prevent certain actions:
import sys
def audit(event, args):
if event == 'compile':
sys.exit('nice try!')
sys.addaudithook(audit)
eval('5')
Additionally, to protect your host OS, use
In the case of containerization with docker you may need to add AppArmor or SELinux policies for extra safety. lxd already comes with AppArmor policies by default.
Make sure you run the code as a user with as little privileges as possible.
Rebuild the virtual machine/container for each user.
Whichever solution you use, don't forget to limit resource usage (RAM, CPU, storage, network). Use cgroups if your chosen virtualization/containerization solution does not support these kinds of limits.
Last but not least, use timeouts to prevent your users' code from running forever.