I am developing a quite large web application, and it is probably a good idea to use hotkeys for some common tasks. However, I discovered that finding safe key combinations is a problem, regarding all different browsers and OSes.
For example, Chrome has such a long list of hotkeys that trying to use some kind of logical hotkeys scheme for my web application is impossible - e.g. Ctrl + 1, Ctrl + 2, Ctrl + 3, etc.
Do you have some cheat sheet of safe hotkeys which can be used in a web application and not worry about some browser or OS interference?