Give the element an id, do the following in Javascript (I am assuming you have JQuery, your question itself is lacking details in many ways as I write this right now, you should really try to give more information in order to get answers).
EDIT: My solution to the iframe/jquery issue would be to use a video element instead of an iframe. Here is how: Show Youtube video source into HTML5 video tag?
We would then continue to use the below JS/JQuery
Example JQuery:
$('play').on("click", function() {
//Do something
});
Example with shortcut implemented:
$('play').click(function() {
//Do something
});