I am building an iOS app that transmits sensitive data to my server, and I'm signing my API requests as an additional measure. I want to make reverse engineering as hard as possible, and having used Cycript to find signing keys of some real-world apps, I know it's not hard to find these keys by attaching to a process. I am absolutely aware that if someone is really skilled and tries hard enough, they eventually will exploit, but I'm trying to make it as hard as possible, while still being convenient for myself and users.
I can check for jailbroken status and take additional measures, or I can do SSL pinning, but both are still easy to bypass by attaching to the process and modifying the memory.
Is there any way to detect if something (whether it be Cycript, gdb, or any similar tool that can be used for cracking the process) is attached to the process, while not being rejected from App Store?
EDIT: This is not a duplicate of Detecting if iOS app is run in debugger. That question is more related to outputting and it checks an output stream to identify if there's an output stream attached to a logger, while my question is not related to that (and that check doesn't cover my condition).