I started to have this issue after migrate from eclipse to AS. When i run one app for the first time, it's running normally....but after 5 ~ 10 run...my device stop to respond to any touch/button press (only hold the power works)...and even removing the USB, my device run any app very very slow.
I already tried this topics:
http://www.viralandroid.com/2015/08/how-to-make-android-studio-fast.html
Building and running app via Gradle and Android Studio is slower than via Eclipse
i put this on manifest
android:vmSafeMode="true"
and no one works. Anyone knows why it happens?