In the normal situation, Sikuli scripts use the machine's screen, mouse and keyboard, so while a script is running, the machine may not be used.
In this other Sikuli question about headless mode, a virtual screen is added to a second (headless) machine so that Sikuli scripts can operate there.
This question is about doing it all on one machine. Has a specific software stack and configuration been defined that (presumably) utilizes the same or similar techniques* such that a single Windows 7 machine can initiate a Sikuli script (using an alternate screen, keyboard, mouse combination) and still allow the "real" screen, keyboard and mouse to be used concurrently with the running script.
* virtual screen and/or both VNC client and server on the same machine, etc.