I like to check out what The Queen of Indexing, Kimberly Tripp, has to say on the topic:
I'm going to start with my recommendation for the Clustering Key - for a couple of reasons. First, it's an easy decision to make and second, making this decision early helps to proactively prevent some types of fragmentation. If you can prevent certain types of base-table fragmentation then you can minimize some maintenance activities (some of which, in SQL Server 2000 AND less of which, in SQL Server 2005) require that your table be offline. OK, I'll get to the rebuild stuff later.....
Let's start with the key things that I look for in a clustering key:
* Unique
* Narrow
* Static
Why Unique?
A clustering key should be unique because a clustering key (when one exists) is used as the lookup key from all non-clustered indexes. Take for example an index in the back of a book - if you need to find the data that an index entry points to - that entry (the index entry) must be unique otherwise, which index entry would be the one you're looking for? So, when you create the clustered index - it must be unique. But, SQL Server doesn't require that your clustering key is created on a unique column. You can create it on any column(s) you'd like. Internally, if the clustering key is not unique then SQL Server will “uniquify” it by adding a 4-byte integer to the data. So if the clustered index is created on something which is not unique then not only is there additional overhead at index creation, there's wasted disk space, additional costs on INSERTs and UPDATEs, and in SQL Server 2000, there's an added cost on a clustereD index rebuild (which because of the poor choice for the clustering key is now more likely).
Source: Ever-increasing clustering key debate - again!