U-SQL does not support dynamic U-SQL at this point although if you feel this is an important missing feature you could post a feature request here:
https://feedback.azure.com/forums/327234-data-lake
It looks like there is already a similar request you can vote for here.
As a workaround, you could generate the U-SQL dynamically then run the script separately either manually or using one of the SDKs eg using Powershell, .net. A simple example:
//Dynamic U-SQL
DECLARE @viewName string = "dbo.vw_yourViewName";
// Create dynamic U-SQL
@usql =
SELECT *
FROM ( VALUES
( "USE DATABASE yourDatabase;"),
( String.Format("DROP VIEW IF EXISTS {0};", @viewName)),
( String.Format("CREATE VIEW IF NOT EXISTS {0} AS EXTRACT col1 int, col2 string, col3 string, col4 string, col5 string FROM \"/input/input44.txt\" USING Extractors.Csv();", @viewName))
) AS x (usql);
// Output the statements in the correct sort order
OUTPUT @usql
TO "/output/dynamic.usql"
USING Outputters.Text(delimiter:' ', quoting:false);
Other examples of dynamic U-SQL (or more precisely, U-SQL generated dynamically) are here and here.