Leading ampersand is ignored by the current version of the compiler, pretty much in the same way as the last ;
is ignored inside interface declaration:
interface a {
a(): string;
}
type b = & a;
TypeScript playground says type b = a
The typings linked from the question are (ab)using this feature to have more uniform syntax for intersection types:
export type CSSProperties =
& ObservableProperties<csstype.Properties>
& ObservableProperties<csstype.PropertiesHyphen>;
When written this way, when you remove the first intersection member for example, you can just delete the whole line and you don't have to change anything else.