I found sometimes the ProjectTypeGuids is missing in C# projects and sometimes not.
<ProjectTypeGuids>{3AC096D0-A1C2-E12C-1390-A8335801FDAB};{FAE04EC0-301F-11D3-BF4B-00C04F79EFBC}</ProjectTypeGuids>
I didn't see any impact if it is missing. While seeing some guys were also asking the significance of it, i always notice this link below shared in the answers which shows the list of ProjectTypeGuids defined by MS.
List of Visual Studio Project Type GUIDs
Unfortunately, very few information is given by MS besides the post below where one MS employee answered it was for project aggregation. But who knows what project aggregation means.
What is the significance of ProjectTypeGuids tag in the visual studio project file