I need to update the given Excel into MySql database using C# and .Net Framework
Can anyone help me in providing the reference links,so that i can learn and implement the same.
This isn't question for stack overflow, but to get you started (and in future to return to SO and ask specific question with code sample :))
For reading and writing Excel files, it would be the easiest to use NPOI, .net port of Apache POI.
Then, google a bit and you can find a lot of examples like this one or maybe this one
To access MySQl you have everything you need in .NET framework or you can use MySQL Connector. Of course, there are a lot of samples, especially on stack owerflow