Basically, build an array of your test values, and loop that array until you find something.
Something like this
Sub Demo()
Dim ws As Worksheet
Dim rTestStings As Range, TestStings As Variant
Dim TestValue As Variant
Dim idx As Long
Dim Found As Boolean
'Get Test Strings from Sheet. Adjust to suit your data
With rTestStings = Worksheets("specific sheet")
Set rTestStings = .Range(.Cells(1, 1), .Cells(.Rows.Count, 1).End(xlUp))
End With
TestStings = rTestStings.Value2
Set ws = Sheets("Le 2250")
'I'm guessing you are doing something like this
For i = SomeValue To SomeOtherValue
TestValue = ws.Cells(i, 1).Value
Found = False
For idx = LBound(TestStings, 1) To UBound(TestStings, 1)
If Not IsEmpty(TestStings(idx, 1)) Then 'incase there are gaps in your test data
If InStr(TestValue, TestStings(idx, 1)) Then
Found = True
Exit For
End If
End If
Next
If Found Then
MsgBox "Found " & TestStings(idx, 1) & " in cell " & ws.Cells(i, 1).Address
' do something ...
End If
Next i
End Sub