I'm using lightbox2 to display a data uri on Edge/IE11. Tiny images work fine while larger images(Not huge) get cut off at some point. Edge/IE don't have full support for data URI's but, if you use the debugger to cut paste the data uri from the href to the img tag the image will display fine. For some reason in moving the data from the href to the img tag it is cut off.
<html>
<head>
<link rel="stylesheet" href="/path/to/lightbox.css">
<script src="libs/jquery/3.3.1/jquery.min.js"> </script>
<script src="/path/to/lightbox.js"></script>
</head>
<body>
<a href="data:image/png;base64,…" data-lightbox="image-1" data-title="My caption">Image #1</a>
</body>
</html>