This is really a question for CrossValidated rather than a Python question.
Your data seems to strongly indicate a simple underlying model which is linear until the very end, when it perhaps becomes polynomial.
As a first step, if possible, I would investigate this phenomenon. It's unusual. Perhaps there's something wrong with the data source. But maybe not. For example, a physical phenomenon with two distinct phases might produce data like these.
As to models, I would suggest natural cubic splines for this data. They are simple and involve cutting the data up into windows which you fit with cubic polynomials (a special case of which is a line).
You might also consider smoothing splines, and local regression.
For information on these, see the free online textbook, An Introduction to Statistical Learning.