lastRow = .Cells(Rows.Count, 4).End(xlUp).row
I never use this method for figuring out last row. It takes too long... Basically processing every cell starting from the bottom of the worksheet. Instead, I count the number of cells with values. I use that number to run a for loop which tests to see if there is a value in a given cell and counts until all cells with values are accounted for. Code wise, its more complicated... but in my experience executes more quickly.
kount = Application.WorksheetFunction.CountA(krng) 'Count how many used cells there are
kRow = 1
j = 1
Do Until j = kount + 1 'Do until all used cells are acounted for
If Cells(kRow, l).Value = vbNullString Then 'If current cell is empty skip it
Else
j = j + 1 'If the current cell has a value count up
End If
kRow = kRow + 1 'but go on to the next row either way
Loop
Where kRow is the last row with a value