Which folders should I remove after uninstalling Anaconda on Windows 10?

Question

[Prehistory: I have a lot of bugs in my Anaconda Installation (like Spyder not opening, not being able to install certain packages and so on). I think this problems occur because I installed it when python 3.7 was very new and not compatible with other stuff.]

Therefore I uninstalled Anaconda from Windows 10 using

• Uninstall-Anaconda.exe in C:\Users\username\Anaconda3

like suggested in https://stackoverflow.com/a/39490516/7735095.

After doing so I fave found out that there would have been a better removal method:

• executing:

  conda install anaconda-clean
  anaconda-clean
  

  BEFORE uninstalling Anaconda,

like suggested in https://docs.anaconda.com/anaconda/install/uninstall/. But now it is too late for it because I already uninstalled Anaconda the classical way.

So my question is? What should I remove now manually?

For example in C:\Users\jakob I still have the folders:

.anaconda
.conda
.ipython
.jupyter
.matplotlib
.spyder-py3

and the file:

.condarc

Can I destroy anything when I delete those folders and this file? Why did the default uninstall leave them on my system?

What about:

C:\Users\jakob\AppData\Local\conda
C:\Users\jakob\AppData\Local\Spyder

C:\Users\jakob\AppData\Roaming\jupyter
C:\Users\jakob\AppData\Roaming\Jedi

C:\Users\jakob\AppData\Local\Packages\Microsoft.MicrosoftEdge_8wekyb3d8bbwe\AC\#!001\MicrosoftEdge\User\Default\DOMStore\YP1KVEAM\conda[1].xml
C:\Users\jakob\AppData\Local\Packages\Microsoft.MicrosoftEdge_8wekyb3d8bbwe\AC\#!121\MicrosoftEdge\User\Default\DOMStore\0KLIGYWH\conda[1].xml

Can I delete all of them?

In my registry I still have:

Computer\HKEY_CURRENT_USER\Software\Python\PythonCore

Is it dangerous to delete it from the registry? Why did Uninstall-Anaconda.exe leave it on my system?

Do you think there are further traces of Anaconda that could be removed?