Since this is tagged "embedded", I assume its for embedded systems?
In that case, the major difference between C and C++ is the way C++ treats structs. All structs will be treated like classes, meaning they will have constructors.
All instances of structs/classes declared at file scope or as static will then have their constructors called before main() is executed, in a similar manner to static initialization, which you already have there no matter C or C++.
All these constructor calls at bootup is a major disadvantage in efficiency for embedded systems, where the code resides in NVM and not in RAM. Just like static initialization, it will create an ugly, undesired workload peak at the start of the program, where values from NVM are copied into the RAM.
There are ways around the static initialization in C/C++: most embedded compilers have an option to disable it. But since that is a non-standard setup, all code using statics would then have to be written so that it never uses any initialization values, but instead sets all static variables in runtime.
But as far as I know, there is no way around calling constructors, without violating the standard.
EDIT:
Here is source code executed in one such C++ system, Freescale HCS08 Codewarrior 6.3. This code is injected in the user program after static initialization, but before main() is executed:
static void Call_Constructors(void) {
int i;
...
i = (int)(_startupData.nofInitBodies - 1);
while (i >= 0) {
(&_startupData.initBodies->initFunc)[i](); /* call C++ constructors */
i--;
}
...
At the very least, this overhead code must be executed at program startup, no matter how efficient the compiler is at converting constructors into static initializtion.