Will IIS hosted web service take more time to respond than self hosted service?

Question

I have microservices, all are deployed in IIS. When I trigger request to those services taking 2k+ millisecond for each and every request. But, If I run those services using IIS Express and self hosted way(for wcf) I got response in 100 millisecond. Verified time using Postman.

Already tried some basic verification like , App Pool recycling (1740 minutes) StartMode(Always Running) PreEnabled(True) AppInitialization also set.

Can anyone suggest solution for this problem?

WCF implementation here,

<?xml version="1.0" encoding="utf-8"?>
<configuration>
  <configSections>
    <section name="entityFramework" type="System.Data.Entity.Internal.ConfigFile.EntityFrameworkSection, EntityFramework, Version=6.0.0.0, Culture=neutral, PublicKeyToken=b77a5c561934e089" requirePermission="false" />
    <!-- For more information on Entity Framework configuration, visit http://go.microsoft.com/fwlink/?LinkID=237468 -->
  </configSections>
  <connectionStrings>

  </connectionStrings>
  <system.web>
    <compilation debug="true" targetFramework="4.7.2" />
    <httpRuntime targetFramework="4.6.1" />
  </system.web>
  <system.serviceModel>
    <services>
      <service name="CalculationService">
        <endpoint address="rest" behaviorConfiguration="CalculationServiceAspNetAjaxBehavior" bindingConfiguration="webHttpBinding_IMyService" binding="webHttpBinding" contract="ICalculationService" />
        <endpoint address="" binding="basicHttpBinding" contract="ICalculationService" />
        <endpoint address="mex" binding="mexHttpBinding" contract="IMetadataExchange" />
        <host>
          <baseAddresses>
            <add baseAddress="http://ip/CalculationService" />
          </baseAddresses>
        </host>
      </service>
    </services>
    <bindings>
      <webHttpBinding>
        <binding name="webHttpBinding_IMyService" maxBufferPoolSize="524288000" maxBufferSize="524288000" maxReceivedMessageSize="524288000">
          <readerQuotas maxDepth="524288000" maxStringContentLength="524288000" maxArrayLength="524288000" maxBytesPerRead="524288000" maxNameTableCharCount="524288000" />
          <security mode="None" />
        </binding>
      </webHttpBinding>
    </bindings>
    <behaviors>
      <endpointBehaviors>
        <behavior name="CalculationService.CalculationServiceAspNetAjaxBehavior">
          <webHttp defaultOutgoingResponseFormat="Json" helpEnabled="true" faultExceptionEnabled="true" />
        </behavior>
      </endpointBehaviors>
      <serviceBehaviors>
        <behavior name="">
          <serviceMetadata httpGetEnabled="true" />
          <serviceDebug includeExceptionDetailInFaults="true" />
        </behavior>
      </serviceBehaviors>
    </behaviors>
    <protocolMapping>
      <add binding="basicHttpsBinding" scheme="http" />
      <add binding="webHttpBinding" scheme="http" />
    </protocolMapping>
    <serviceHostingEnvironment aspNetCompatibilityEnabled="false" multipleSiteBindingsEnabled="true" />
  </system.serviceModel>
  <system.webServer>
    <modules runAllManagedModulesForAllRequests="true" />
    <directoryBrowse enabled="true" />
  </system.webServer>
  <entityFramework>
    <defaultConnectionFactory type="System.Data.Entity.Infrastructure.LocalDbConnectionFactory, EntityFramework">
      <parameters>
        <parameter value="mssqllocaldb" />
      </parameters>
    </defaultConnectionFactory>
    <providers>
      <provider invariantName="System.Data.SqlClient" type="System.Data.Entity.SqlServer.SqlProviderServices, EntityFramework.SqlServer" />
    </providers>
  </entityFramework>

  <runtime>
    <assemblyBinding xmlns="urn:schemas-microsoft-com:asm.v1">
      <dependentAssembly>
        <assemblyIdentity name="System.Runtime.CompilerServices.Unsafe" publicKeyToken="b03f5f7f11d50a3a" culture="neutral" />
        <bindingRedirect oldVersion="0.0.0.0-4.0.4.1" newVersion="4.0.4.1" />
      </dependentAssembly>
      <dependentAssembly>
        <assemblyIdentity name="System.Memory" publicKeyToken="cc7b13ffcd2ddd51" culture="neutral" />
        <bindingRedirect oldVersion="0.0.0.0-4.0.1.1" newVersion="4.0.1" />
      </dependentAssembly>
      <dependentAssembly>
        <assemblyIdentity name="System.Buffers" publicKeyToken="cc7b13ffcd2ddd51" culture="neutral" />
        <bindingRedirect oldVersion="0.0.0.0-4.0.2.0" newVersion="4.0.2.0" />
      </dependentAssembly>
    </assemblyBinding>
  </runtime>