When a client invokes my REST-ful service, it needs to know if the response came back was 'from me' or rather a diagnosis from the containing web server that something awful happened.
One theory is that, if my code is called, it should always return an HTTP OK(=200), and any errors I've got to return should be just represented in the data I return. After all, it's my code that gets the response, not the naked browser.
Somewhat self-evidently, if I'm using REST to generate HTML read directly by a browser, I absolutely must return an error code if there's an error. In the case I care about, it's always Javascript or Java that is interpreting the entrails of the response.
Another possibility is that there is some family of HTTP status codes that I could return with a high confidence that it/they would never be generated by a problem in the surrounding container. Is this the case?