Yes, there is. You could use the group_by_at
function:
mtcars %>% group_by_at(vars(starts_with("c"), gear))
Group by all columns whose name starts with "c" and by the column gear
Output
# A tibble: 32 x 11
# Groups: cyl, carb, gear [12]
mpg cyl disp hp drat wt qsec vs am gear carb
<dbl> <dbl> <dbl> <dbl> <dbl> <dbl> <dbl> <dbl> <dbl> <dbl> <dbl>
1 21 6 160 110 3.9 2.62 16.5 0 1 4 4
2 21 6 160 110 3.9 2.88 17.0 0 1 4 4
3 22.8 4 108 93 3.85 2.32 18.6 1 1 4 1
4 21.4 6 258 110 3.08 3.22 19.4 1 0 3 1
5 18.7 8 360 175 3.15 3.44 17.0 0 0 3 2
6 18.1 6 225 105 2.76 3.46 20.2 1 0 3 1
7 14.3 8 360 245 3.21 3.57 15.8 0 0 3 4
8 24.4 4 147. 62 3.69 3.19 20 1 0 4 2
9 22.8 4 141. 95 3.92 3.15 22.9 1 0 4 2
10 19.2 6 168. 123 3.92 3.44 18.3 1 0 4 4
# ... with 22 more rows