when client(typically browser)visit a web server(like nodejs based server you used), a session was built between client and server. As far as i know, session stores on the server side, normally it will send back the session's id(named sessionId or jsessionid ...), then web connection was built.
So if you would like to remove a session on the client side, you just need to remove the sessionId attribute's value in the cookie with this
document.cookie = "sessionIdKey=;"
you should replace 'sessionIdKey' with the key in your chrome dev tools => application => cookies => sitecookie place
this will end session connection, when this session time out, server will delete the session finally.
update: if you'd like to delete all cookies(sessionid between them), reference this: Clearing all cookies with JavaScript