You can use the below code to switch to frame and then interact with the desired element :-
wait = WebDriverWait(driver, 20)
wait.until(EC.frame_to_be_available_and_switch_to_it((By.XPATH, "//iframe[contains(@sandbox,'allow-popups-to-escape-sandbox')]")))
ele = wait.until(EC.element_to_be_clickable((By.CSS_SELECTOR, "div.analytics-ui-application")))
#ele is a web element so you can trigger .click, .text or any other web element methods on it.
Imports :
from selenium.webdriver.support.ui import WebDriverWait
from selenium.webdriver.common.by import By
from selenium.webdriver.support import expected_conditions as EC