As you have not provided examples of what your expected and current output look like, I'm making some assumptions below. What it seems like you're trying to do is iterate through every value in a column and if the value meets certain conditions, change it to something else.
Just a general pointer. Iterating through dataframes requires some important considerations for larger sizes. Read through this answer for more insight.
Start by defining a function you want to use to check the value:
def has_comma(value):
if ',' in value:
return True
return False
Then use the pandas.DataFrame.replace
method to make the change.
for i in df['column_name']:
if has_comma(i):
df['column_name'] = df['column_name'].replace([i], 'ENM')
else:
df['column_name'] = df['column_name'].replace([i], 'UNM')