Calling sqlite.connect() in Python using in-memory variable instead of file path

Question

Using Python 3.10.8 is it possible to call sqlite.connect() using a variable containing the raw db file instead of a file path on disk? I.E. read the db file from an external source into memory and then call connect() with the variable in memory?

For example:

...
import sqlite3
...


db = s3.get('my-bucket', 'myapp.db')
sqlite.connect(db)