calling a .net 2.0 webservice from .net 4.0 on same iis server

Question

I have two sites, site A running .NET 2.0 and site B .NET 4.0 framework. Both sites are on same IIS server (Windows web server 2008 R2)

Site B calls a webservice on site A. But now after a update it gives an error ("Object reference not set to an instance of an object.").

I allready have attached my sites to two different app pools and the .NET 2.0 site runs fine on its own. Any ideas anyone?

EDIT This is the thrown stacktrace:

Stack Trace:

[NullReferenceException: Object reference not set to an instance of an object.]
   CMyClass.ReScan() +309
   modGlobal.InitializeGlobal(String querystring, String callerIP) +823
   masterFront.Page_Load(Object sender, EventArgs e) +97
   System.Web.UI.Control.LoadRecursive() +70
   System.Web.UI.Control.LoadRecursive() +189
   System.Web.UI.Page.ProcessRequestMain(Boolean includeStagesBeforeAsyncPoint, Boolean includeStagesAfterAsyncPoint) +3063

Not sure what +309 refers to, There are no line 309 in ReScan?

The issue is probably completely not related to the .NET 2.0 vs .NET 4.0 issue but rather with a bug in your InitializeGlobal method in the modGlobal class. You probably are not enough defensive there. — Wiktor Zychla, Oct 27 '11 at 18:33
Show the actual code that calls it, and show the line where the NullReferenceException occurs. — John Saunders, Oct 27 '11 at 19:23
@John Saunders How do I find the code that throws the expection. By the way, its running perfectly localy (windows 7) and on my development server (windows server 2003) — Muleskinner, Oct 27 '11 at 19:32
See http://stackoverflow.com/questions/4660142/what-is-a-nullreferenceexception-in-net — John Saunders, Oct 27 '11 at 21:01
@John Saunders Not sure what +309 refers to, There are no line 309 in ReScan? — Muleskinner, Oct 27 '11 at 22:11
It's not a line number. It means 309 bytes past the start of the method. More importantly, go read that question I linked, then look at your code with that in mind. Under some circumstance, you're referencing something you haven't set. — John Saunders, Oct 27 '11 at 22:17

calling a .net 2.0 webservice from .net 4.0 on same iis server

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