For OpenCOBOL, there is an embedded Tcl/Tk layer by Rildo Pragana (author of TinyCOBOL, his TC Tcl/Tk sample compiled and linked for OpenCOBOL, first try), but if you don't like Tcl/Tk, his toolkit places almost all of the GUI on the Tk side, so:
- There is also a GTK+ layer sample

Source code looking like:
*> Add a text entry field
CALL "CBL_OC_GTK_ENTRY_NEW"
returning gtk-textentry
END-CALL
*> Connect code to the text entry, passing the entry widget
SET callback TO ENTRY "CBL_OC_activate"
CALL "CBL_OC_G_SIGNAL_CONNECT"
using by value gtk-textentry
by reference "activate" & x"00"
by value callback
by value gtk-textentry
END-CALL
...
*> window is ready to show
CALL "CBL_OC_GTK_WIDGET_SHOW"
using by value gtk-window
END-CALL
*> Start up the event loop, control returned when GTK main exits
CALL "CBL_OC_GTK_MAIN" END-CALL
*> Something terminated the GTK main loop, sys-close or bye or
display "ending..." end-display
- FLTK worked, but I haven't posted the trial source codes.
- GtkHTML widgets worked too.
- A Gambas COBOL GUI layer is hosted on Google Code
- ROOT/CINT can interpret OpenCOBOL generated C, and then you can get interactive graphs from WORKING-STORAGE.
- Qt tested fine, but C++ requires more, albeit thin, wrapper source, so GTK was targeted instead.
Pretty much anything that can be wrapped by C, can be called by OpenCOBOL. That includes the native Microsoft WinAPI.
While working on the FAQ I found that using Vala really opens up the field for extending COBOL. As both OpenCOBOL and Vala produce intermediate C, the mixing potential is nearly unlimited, and developers can benefit from efforts by either project. I recommend checking out Vala for use from COBOL.
See the OpenCOBOL FAQ, section 5 for working samples. Screen capture image from source code listed at http://opencobol.add1tocobol.com/#does-opencobol-support-the-gimp-toolkit-gtk