A couple of thoughts spring to mind -
Firstly implement a post quality control system. This is up to you, but perhaps something like a minimum character/word limit? Obviously a one-word comment might be completely acceptable, so it's up to yourself. Another alternative might be a regular expression to confirm the post contains at least one valid English (?) word, or a search against a known list of blacklisted websites.
A nice little bit of server-side validation could handle that in MVC :)
Secondly you can implement a time limit on new posts, nothing huge perhaps only a few milliseconds, or a second or so. It helps mitigate a denial of service, since any request from a particular IP address will basically not be processed if it comes too closely behind another. This is perhaps something that would be dealt with again in server-side validation but outside of the controller - a separate set of classes would be responsible for keeping track of what was posted and what constitutes a 'spammy' comment based on timeframe.
A third option would be to implement the dreaded CAPTCHA (perhaps ReCaptcha) on each comment, although from a Usability perspective that would really be annoying for users ;) Easy to implement and lots of details on the ReCaptcha site, including .Net libraries IIRC.
A fourth option might be to include a comment moderation system, so comments must be approved by the OP before they appear. Very similar to most blogs.
A fifth option could be a facility to ban based on IP addresses to help cut out known spammers. Similarly there are various APIs out there to help filter comments based on spamminess of content such as Akismet.
It's a pretty big topic, so sorry for the general-purpose nature of the suggestions. I hope a couple might be useful :)