I'm busy with the database design of a new project, and I'm not sure whether to use UUIDs or normal table-unique auto-increment ids.
Up to now, the sites I've built have all run on a single server, and very heavy traffic has never been too much of a concern. However, this web application will eventually run concurrently on multiple servers, serve an API, and need to process thousands of requests per second, and I want to make sure that the design I choose now doesn't cripple any of those possibilities later.
I have my suspicions, of course, and they should be clear through the way I phrased my question, but I would like to hear from those with more experience what trouble I can run into later if I do or don't have UUIDs, and what I should really be basing my decision on.
So, in short: What are the considerations I should give into deciding whether or not to use UUIDs for all database models, so that any one object can be identified uniquely by one string, and when is it appropriate to use this as the primary key, instead of table-by-table auto-increment?
Note: I've seen this question (When are you truly forced to use UUID as part of the design?), and read all the answers, but they mostly answer "How rarely do UUIDs collide", instead of "When is it appropriate to use them".