Not impossible as the top answer suggests. I have the same problem as OP. I have some sources for cross compiling for a raspberry pi pico, and then some unit tests that I am running on my host system.
To make this work, I'm using the very shameful "set" to override the compiler in the CMakeLists.txt for my test folder. Works great.
if(DEFINED ENV{HOST_CXX_COMPILER})
set(CMAKE_CXX_COMPILER $ENV{HOST_CXX_COMPILER})
else()
set(CMAKE_CXX_COMPILER "g++")
endif()
set(CMAKE_CXX_FLAGS "")
The cmake devs/community seems very against using set to change the compiler since for some reason. They assume that you need to use one compiler for the entire project which is an incorrect assumption for embedded systems projects.
My solution above works, and fits the philosophy I think. Users can still change their chosen compiler via environment variables, if it's not set then I do assume g++
. set only changes variables for the current scope, so this doesn't affect the rest of the project.