Google App Engine Python Runtime Environment.
App Engine executes Python application code using a pre-loaded Python interpreter in a safe "sandboxed" environment. The python app receives web requests, performs work, and sends responses by interacting with this environment.
A Python web app interacts with the App Engine web server using the WSGI protocol, so apps can use any WSGI-compatible web application framework. App Engine includes a simple web application framework, called webapp2, to make it easy to get started. For larger applications, mature third-party frameworks, such as Django, work well with App Engine.