For questions about the TypeScript compiler for the Google Closure Javascript framework.
The Google Closure is a a strongly-typed extension of the Javascript language, and also a Javascript obfuscator and optimizer. Contrary the better known Typescript, it uses remarks for the typing metadata.
Typescript uses the tsc (typescript compiler) to generate Javascript code. Its optimization possibilities are below of the Google Closure Compiler.
Tsickle converts TypeScript code into a form acceptable to the Closure Compiler. Large frameworks (Angular) can not be compiled with tsickle today. In the case smaller projects, it can reach a huge size decrease and speed improvement to the common solutions (tsc + webpack).
References