ABCA8
Identifiers
AliasesABCA8, ATP binding cassette subfamily A member 8
External IDsOMIM: 612505 MGI: 1351668 HomoloGene: 56029 GeneCards: ABCA8
Orthologs
SpeciesHumanMouse
Entrez

10351

27404

Ensembl

ENSG00000141338

ENSMUSG00000020620

UniProt

O94911

Q8K440

RefSeq (mRNA)

NM_001288985
NM_001288986
NM_007168
NM_001375771
NM_001375772

NM_013851
NM_001362749

RefSeq (protein)

NP_001275914
NP_001275915
NP_009099
NP_001362700
NP_001362701

NP_038879
NP_001349678

Location (UCSC)Chr 17: 68.87 – 68.96 MbChr 11: 109.82 – 109.89 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

ATP-binding cassette sub-family A member 8 is a protein that in humans is encoded by the ABCA8 gene.[5]

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The function of this protein has not yet been determined.[5]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000141338 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000020620 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. 1 2 "Entrez Gene: ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8".

Further reading



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