GABRG3
Identifiers
AliasesGABRG3, gamma-aminobutyric acid type A receptor gamma3 subunit, gamma-aminobutyric acid type A receptor subunit gamma3
External IDsOMIM: 600233 MGI: 95624 HomoloGene: 22444 GeneCards: GABRG3
Orthologs
SpeciesHumanMouse
Entrez

2567

14407

Ensembl

ENSG00000182256

ENSMUSG00000055026

UniProt

Q99928

P27681

RefSeq (mRNA)

NM_001270873
NM_033223

NM_008074
NM_177273

RefSeq (protein)

NP_001257802
NP_150092

NP_032100

Location (UCSC)Chr 15: 26.97 – 27.54 MbChr 7: 56.37 – 57.04 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

GABAA receptor-γ3, also known as GABRG3, is a protein which in humans is encoded by the GABRG3 gene.

Function

GABRG3 is a subunit of the GABAA receptor for the neurotransmitter gamma-Aminobutyric acid (GABA).[5]

Association with alcoholism

Genetic markers near the GABRG3 gene are statistically linked to alcoholism.[6]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000182256 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000055026 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3".
  6. Dick DM, Edenberg HJ, Xuei X, Goate A, Kuperman S, Schuckit M, Crowe R, Smith TL, Porjesz B, Begleiter H, Foroud T (January 2004). "Association of GABRG3 with alcohol dependence". Alcohol. Clin. Exp. Res. 28 (1): 4–9. CiteSeerX 10.1.1.418.2528. doi:10.1097/01.ALC.0000108645.54345.98. PMID 14745296.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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