PEX3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPEX3, PBD10A, TRG18, peroxisomal biogenesis factor 3, PBD10B
External IDsOMIM: 603164 MGI: 1929646 HomoloGene: 2691 GeneCards: PEX3
Orthologs
SpeciesHumanMouse
Entrez

8504

56535

Ensembl

ENSG00000034693

ENSMUSG00000019809

UniProt

P56589
Q7Z6V3

Q9QXY9

RefSeq (mRNA)

NM_003630

NM_001164195
NM_019961
NM_001347361

RefSeq (protein)

NP_003621

NP_001157667
NP_001334290
NP_064345

Location (UCSC)Chr 6: 143.45 – 143.49 MbChr 10: 13.4 – 13.43 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Peroxisomal biogenesis factor 3 is a protein that in humans is encoded by the PEX3 gene.[5][6]

Interactions

PEX3 has been shown to interact with PEX19.[7][8][9][10]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000034693 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000019809 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Kammerer S, Holzinger A, Welsch U, Roscher AA (Jun 1998). "Cloning and characterization of the gene encoding the human peroxisomal assembly protein Pex3p". FEBS Letters. 429 (1): 53–60. doi:10.1016/S0014-5793(98)00557-2. PMID 9657383. S2CID 33291739.
  6. "Entrez Gene: PEX3 peroxisomal biogenesis factor 3".
  7. Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
  8. Mayerhofer PU, Kattenfeld T, Roscher AA, Muntau AC (Mar 2002). "Two splice variants of human PEX19 exhibit distinct functions in peroxisomal assembly". Biochemical and Biophysical Research Communications. 291 (5): 1180–6. doi:10.1006/bbrc.2002.6568. PMID 11883941.
  9. Sacksteder KA, Jones JM, South ST, Li X, Liu Y, Gould SJ (Mar 2000). "PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis". The Journal of Cell Biology. 148 (5): 931–44. doi:10.1083/jcb.148.5.931. PMC 2174547. PMID 10704444.
  10. Fransen M, Wylin T, Brees C, Mannaerts GP, Van Veldhoven PP (Jul 2001). "Human pex19p binds peroxisomal integral membrane proteins at regions distinct from their sorting sequences". Molecular and Cellular Biology. 21 (13): 4413–24. doi:10.1128/MCB.21.13.4413-4424.2001. PMC 87101. PMID 11390669.

Further reading


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