First of all your Database structure is not normalized and should have been. Since it is already set up this way , here's how to solve the issue.
You'll need a function to split your string first:
CREATE FUNCTION SPLIT_STRING(str VARCHAR(255), delim VARCHAR(12), pos INT) RETURNS VARCHAR(255)
RETURN REPLACE(SUBSTRING(SUBSTRING_INDEX(str, delim, pos),
LENGTH(SUBSTRING_INDEX(str, delim, pos-1)) + 1), delim, '');
Then you'll need to create a view in order to make up for your structure:
CREATE VIEW database.viewname AS
SELECT SPLIT_STRING(CourseID, ',', n) as firstField,
SPLIT_STRING(CourseID, ',', n) as secondField,
SPLIT_STRING(CourseID, ',',n) as thirdField
FROM 1stTable;
Where n is the nth item in your list.
Now that you have a view which generates your separated fields, you can make a normal join on your view, just use your view like you would use a table.
SELECT *
FROM yourView
JOIN table1.field ON table2.field
However since I don't think you'll always have 3 values in your second field from your first table you'll need to tweak it a little more.
Inspiration of my answer from:
SQL query to split column data into rows
and
Equivalent of explode() to work with strings in MySQL