ZBTB17
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesZBTB17, MIZ-1, ZNF151, ZNF60, pHZ-67, zinc finger and BTB domain containing 17
External IDsOMIM: 604084 MGI: 107410 HomoloGene: 2575 GeneCards: ZBTB17
Orthologs
SpeciesHumanMouse
Entrez

7709

22642

Ensembl

ENSG00000116809

ENSMUSG00000006215

UniProt

Q13105

Q60821

RefSeq (mRNA)

NM_009541
NM_001378826
NM_001378827
NM_001378828

RefSeq (protein)

NP_033567
NP_001365755
NP_001365756
NP_001365757

Location (UCSC)Chr 1: 15.94 – 15.98 MbChr 4: 141.17 – 141.2 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc finger and BTB domain-containing protein 17 is a protein that in humans is encoded by the ZBTB17 gene.[5]

Interactions

ZBTB17 has been shown to interact with TOPBP1,[6] Host cell factor C1[7] and Myc.[8][9]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000116809 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000006215 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: ZBTB17 zinc finger and BTB domain containing 17".
  6. Herold S, Wanzel M, Beuger V, Frohme C, Beul D, Hillukkala T, Syvaoja J, Saluz HP, Haenel F, Eilers M (Sep 2002). "Negative regulation of the mammalian UV response by Myc through association with Miz-1". Molecular Cell. 10 (3): 509–21. doi:10.1016/S1097-2765(02)00633-0. PMID 12408820.
  7. Piluso D, Bilan P, Capone JP (Nov 2002). "Host cell factor-1 interacts with and antagonizes transactivation by the cell cycle regulatory factor Miz-1". The Journal of Biological Chemistry. 277 (48): 46799–808. doi:10.1074/jbc.M206226200. PMID 12244100.
  8. Staller P, Peukert K, Kiermaier A, Seoane J, Lukas J, Karsunky H, Möröy T, Bartek J, Massagué J, Hänel F, Eilers M (Apr 2001). "Repression of p15INK4b expression by Myc through association with Miz-1". Nature Cell Biology. 3 (4): 392–9. doi:10.1038/35070076. PMID 11283613. S2CID 12696178.
  9. Peukert K, Staller P, Schneider A, Carmichael G, Hänel F, Eilers M (Sep 1997). "An alternative pathway for gene regulation by Myc". The EMBO Journal. 16 (18): 5672–86. doi:10.1093/emboj/16.18.5672. PMC 1170199. PMID 9312026.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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